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Driven by the need of non-invasive diagnosis in clinical practice, behavioral screening and tests have attracted more and more research interests recently. Locomotion analysis, as an important division of behavioral tests, has been widely used in diagnostic decision making, comparative biomechanics, biometric identification and forensics, etc. Plenty of instruments and approaches for locomotion analysis...
The aim of metabolic modeling was to understand the cause effect interaction and reliance linked with the complex interactions of biological networks and molecular systems. Drugs that therapeutically modulate the biological processes of disease are often developed with limited knowledge of the underlying complexity of their specific targets. The robustness for systemic modulating behavior of thyroid...
Alzheimer’s disease (AD) is caused by the accumulation of beta-amyloid (β-A) in the brain that forms amyloid plaque. β-A is an oligo-peptide consisting of 39–42 amino acid residues, produced by proteolytic cleavage of amyloid precursor protein by secretase enzymes. Evolutionary trace and protein family analysis of β-A indicates that C-terminal residues of β-A are highly conserved and hydrophobic in...
Medicine is undergoing a revolution that is even transforming the nature of health care from reactive to proactive. To serve these new and diverse needs, bioinformatics and data mining are teaming up to generate tools and procedures for prediction of disease recurrence and progression, response to treatment, as well as new insights into various oncogenic pathways by taking into account the user needs...
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